Publications: Prof. Dr. Wolfgang Liebl

Baudrexl M, Schwarz WH, Zverlov VV, Liebl W (2019) Biochemical characterisation of four rhamnosidases from thermophilic bacteria of the genera Thermotoga, Caldicellulosiruptor and Thermoclostridium. Sci. Rep. 9:15924. doi: 10.1038/s41598-019-52251-0


Rettenmaier R, Liebl W, Zverlov VV (2019) Anaerosphaera multitolerans sp. nov., a salt-tolerant member of the family Peptoniphilaceae isolated from a mesophilically operated biogas fermenter fed with maize silage. Int. J. Syst. Evol. Microbiol., in press. doi: 10.1099/ijsem.0.003903.


Rettenmaier R, Gerbaulet M, Liebl W, Zverlov VV (2019) Hungateiclostridium mesophilum sp. nov., a mesophilic, cellulolytic and spore-forming bacterium isolated from a biogas fermenter fed with maize silage. Int. J. Syst Evol. Microbiol. 69:3567-3573. doi: 10.1099/ijsem.0.003663.


Lichev A, Angelov A, Cucurull I, Liebl W (2019) Amino acids as nutritional factors and (p)ppGpp as an alarmone of the stringent response regulate natural transformation in Micrococcus luteus. Sci. Rep. 9:11030. doi: 10.1038/s41598-019-47423-x


Rykov SV, Kornberger P, Herlet J, Tsurin NV, Zorov IN, Zverlov VV, Liebl W, Schwarz WH, Yarotsky SV, Berezina OV (2019) Novel endo-(1,4)-?-glucanase Bgh12A and xyloglucanase Xgh12B from Aspergillus cervinus belong to GH12 subgroup I and II, respectively. Appl. Microbiol. Biotechnol. 103:7553-7566. doi: 10.1007/s00253-019-10006-x


Rettenmaier R, Duerr C, Liebl W., Zverlov V. (2019) Comparison of sampling techniques and different media for the enrichment and isolation of cellulolytic organisms reveals significant differences. Sys. Appl. Microbiol. 42:481-487. doi: 10.1016/j.syapm.2019.05.002


Rettenmaier R, Neuhaus K, Liebl W, Zverlov VV (2019) Draft genome sequence of Anaerosphaera sp. strain GS7-6-2, a coccal bacterium isolated from a biogas-related environment. Microbiol. Resour. Announc. 8(17). pii: e00205-19. doi: 10.1128/MRA.00205-19.


Burger C, Kessler C, Gruber S, Ehrenreich A, Liebl W, Weuster-Botz D (2019) L-Erythrulose production with a multideletion strain of Gluconobacter oxydans. Appl Microbiol Biotechnol. 103(11):4393-4404. doi: 10.1007/s00253-019-09824-w


Foulquier C, Huang CN, Nguyen NP, Thiel A, Wilding-Steel T, Soula J, Yoo M, Ehrenreich A, Meynial-Salles I, Liebl W, Soucaille P (2019) An efficient method for markerless mutant generation by allelic exchange in Clostridium acetobutylicum and Clostridium saccharobutylicum using suicide vectors. Biotechnol. Biofuels. 12:31. doi: 10.1186/s13068-019-1364-4


Moerch M, Angelov A, Liebl W (2018) Growth-based selection of glycoside hydrolases in the extreme thermophile Thermus thermophilus. Appl. Microbiol. Open Access 4:68–69. DOI: 10.4172/2471-9315-C2-015


Angelov A, Übelacker M, Liebl W (2018) Variances in cellular sedimentation behavior as an effective enrichment method of hydrocarbon-overproducing Micrococcus luteus strains. Biotechnol Biofuels. 11:288. doi: 10.1186/s13068-018-1286-6


Huang C-N, Liebl W, Ehrenreich A (2018) Restriction-deficient mutants and marker-less genomic modification for metabolic engineering of the solvent producer Clostridium saccharobutylicum. Biotechnol. Biofuels 11:264. doi: 10.1186/s13068-018-1260-3


Heinze S, Zimmermann K, Ludwig C, Heinzlmeir S, Schwarz WH, Zverlov VV, Liebl W*, Kornberger P* (2018) Evaluation of promoter sequences for the secretory production of a Clostridium thermocellum cellulase in Paenibacillus polymyxa, Appl. Microbiol. Biotechnol. 102:10147-10159. doi: 10.1007/s00253-018-9369-7 PMID: 30259100


Herlet J, Schwarz WH, Zverlov VV, Liebl W, Kornberger P (2018) Addition of ß-galactosidase boosts the xyloglucan degradation capability of endoglucanase Cel9D from Clostridium thermocellum. Biotechnol Biofuels. 11:238. doi: 10.1186/s13068-018-1242-5 PMID: 30202433


Broeker J, Mechelke M, Baudrexl M, Mennerich D, Hornburg D, Mann M, Schwarz WH, Liebl W, Zverlov VV (2018) The hemicellulose-degrading enzyme system of the thermophilic bacterium Clostridium stercorarium: comparative characterisation and addition of new hemicellulolytic glycoside hydrolases. Biotechnol. Biofuels 11:229. doi: 10.1186/s13068-018-1228-3 PMID: 30159029


Leis B, Held C, Andreeßen B, Liebl W, Graubner S, Schulte L-P, Schwarz WH, Zverlov VV. (2018) Optimizing the composition of a synthetic cellulosome complex for the hydrolysis of softwood pulp: identification of the enzymatic core functions and biochemical complex characterization. Biotechnol. Biofuels 11: 220. doi: 10.1186/s13068-018-1220-y


Heinze S, Kornberger P, Grätz C, Schwarz WH, Zverlov VV, Liebl W (2018) Transmating: conjugative transfer of a new broad host range expression vector to various Bacillus species using a single protocol. BMC Microbiology 18:56. doi: 10.1186/s12866-018-1198-4


Surger MJ, Angelov A, Stier P, Uebelacker M, Liebl W (2018) Impact of branched-chain amino acid catabolism on fatty acid and alkene biosynthesis in Micrococcus luteus. Front. Microbiol. 9:374. doi: 10.3389/fmicb.2018.00374 PMID: 29593665


Zverlov V, Hauf W, Andreeßen B, Bröker J, Graubner S, Liebl W, Schwarz W, Schulte P (2018) Neue Xylanase mit verbesserter Thermostabilität. Patentanmeldung. Amtl. Az. EP17208848.6.


Schwarz WH, Brunecky R, Broeker J, Liebl W, Zverlov VV (2018) Handling gene and protein names in the age of bioinformatics - the special challenge of secreted multimodular bacterial enzymes such as the cbhA/cbh9A gene of Clostridium thermocellum. World J. Microbiol. Biotech. 34:42. doi: 10.1007/s11274-018-2424-9 PMID: 29480332


Pechtl A, Rückert C, Maus I, Koeck DE, Trushina N, Kornberger P, Schwarz WH, Schlüter A, Liebl W, Zverlov VV (2018) Complete Genome Sequence of the Novel Cellulolytic, Anaerobic, Thermophilic Bacterium Herbivorax saccincola Type Strain GGR1, Isolated from a Lab Scale Biogas Reactor as Established by Illumina and Nanopore MinION Sequencing. Genome Announc. 6:e01493-17. doi: 10.1128/genomeA.01493-17 PMID: 29439041


Angelov A, Pham VTT, Übelacker M, Brady S, Leis B, Pill N, Brolle J, Mechelke M, Moerch M, Henrissat B, Liebl W (2017) A metagenome-derived thermostable ß-glucanase with an unusual module architecture which defines the new glycoside hydrolase family GH148. Sci Rep. 7(1):17306.  doi: 10.1038/s41598-017-16839-8 PMID: 29229913


Mechelke M, Herlet J, Benz JP, Schwarz WH, Zverlov VV, Liebl W, Kornberger P (2017) HPAEC-PAD for oligosaccharide analysis-novel insights into analyte sensitivity and response stability. Anal Bioanal Chem. 409:7169-7181. doi: 10.1007/s00216-017-0678-y PMID: 29026979


Zverlov V, Andreeßen B, Graubner S, Kornberger P, Liebl W, Schwarz W, Mechelke M, Herlet J, Schulte P (2017) Herstellung von Oligosacchariden aus Xyloglucan. Patentanmeldung. Amtl. Az. EP17203087.6.


Zverlov V, Hauf W, Andreeßen B, Bröker J, Graubner S, Becker T, Liebl W, Schwarz W (2017) GH10 Xylanasen zur Verbesserung der Prozesszierbarkeit und Produkteigenschaften von pflanzlicher Biomasse. Patentanmeldung. Amtl. Az. EP17202797.1.


Heinze S, Mechelke M, Kornberger P, Liebl W, Schwarz WH, Zverlov VV (2017) Identification of endoxylanase XynE from Clostridium thermocellum as the first xylanase of glycoside hydrolase family GH141. Sci. Rep. 7:11178. doi: 10.1038/s41598-017-11598-y PMID: 28894250


Peters B, Mientus M, Kostner D, Daniel R, Liebl W, Ehrenreich A (2017) Expression of membrane-bound dehydrogenases from a mother of vinegar metagenome in Gluconobacter oxydans. Appl. Microbiol. Biotechnol. 101:7901-7912. doi: 10.1007/s00253-017-8479-y PMID: 28916850


Kostner D, Rachinger M, Liebl W, Ehrenreich A (2017) Markerless deletion of putative alanine dehydrogenase genes in Bacillus licheniformis using a codBA-based counterselection technique. Microbiology 163:1532-1539. doi: 10.1099/mic.0.000544 PMID: 28984230


Leis B, Held C, Bergkemper F, Dennemarck K, Steinbauer R, Reiter A, Mechelke M, Moerch M, Graubner S, Liebl W, Schwarz WH, Zverlov VV. (2017) Comparative characterization of all cellulosomal cellulases from Clostridium thermocellum reveals high diversity in endoglucanase product formation essential for complex activity. Biotechnol Biofuels. 10:240. doi: 10.1186/s13068-017-0928-4 PMID: 29075324


Maus I, Bremges A, Stolze Y, Hahnke S, Cibis KG, Koeck DE, Kim YS, Kreubel J, Hassa J, Wibberg D, Weimann A, Off S, Stantscheff R, Zverlov VV, Schwarz WH, König H, Liebl W, Scherer P, McHardy AC, Sczyrba A, Klocke M, Pühler A, Schlüter A (2017) Genomics and prevalence of bacterial and archaeal isolates from biogas-producing microbiomes. Biotechnol. Biofuels. 10:264. doi: 10.1186/s13068-017-0947-1 PMID: 29158776


Herlet J, Kornberger P, Roessler B, Glanz J, Schwarz WH, Liebl W, Zverlov VV (2017) A new method to evaluate temperature vs. pH activity profiles for biotechnological relevant enzymes. Biotechnol. Biofuels 10:234. doi: 10.1186/s13068-017-0923-9 PMID: 29046720


Mechelke M, Koeck DE, Broeker J, Roessler B, Krabichler F, Schwarz WH, Zverlov VV, Liebl W (2017) Characterization of the arabinoxylan-degrading machinery of the thermophilic bacterium Herbinix hemicellulosilytica - Six new xylanases, three arabinofuranosidases and one xylosidase. J. Biotechnol. 257:122-130. doi: 10.1016/j.jbiotec.2017.04.023 PMID: 28450260


Lewin A, Zhou J, Pham VTT, Haugen T, Zeiny ME, Aarstad O, Liebl W, Wentzel A, Liles MR (2017) Novel archaeal thermostable cellulases from an oil reservoir metagenome. AMB Express. 7:183. doi: 10.1186/s13568-017-0485-z PMID: 28963711


Ehrenreich A, Liebl W (2017) The genomes of acetic acid bacteria. In König H, Unden G, Fröhlich J (Eds) Biology of Microorganisms on Grapes, in Must and in Wine, 2nd edition, Springer International.


Berezina O, Herlet J, Rykov SV, Kornberger P, Zavyalov A, Kozlov D, Sakhibgataeva L, Krestyanova I, Schwarz WH, Zverlov VV, Liebl W, Yarotsky SV (2017) Thermostable multifunctional GH74 xyloglucanase from Myceliophthora thermophila: high-level expression in Pichia pastoris and characterization of the recombinant protein. Appl. Microbiol. Biotechnol. 101:5653-5666. doi: 10.1007/s00253-017-8297-2 PMID: 28477154


Mientus M, Kostner D, Peters B, Liebl W, Ehrenreich A. (2017) Characterization of membrane-bound dehydrogenases of Gluconobacter oxydans 621H using a new system for their functional expression. Appl. Microbiol. Biotechnol. 101:3189-3200. doi: 10.1007/s00253-016-8069-4 PMID: 28064365


Cañete-Rodríguez AM, Santos-Dueñas IM, Jiménez-Hornero JE, Ehrenreich A, Liebl W, García-García I (2016) Gluconic acid production. An excellent example of agro-industrial by-products and wastes revalorization. Process Biochemistry 51:1891-1903.


Bruder LM, Dörkes M, Fuchs BM, Ludwig W, Liebl W. (2016) Flow cytometric sorting of fecal bacteria after in situ hybridization with polynucleotide probes. Syst. Appl. Microbiol. 39(7):464-475. doi: 10.1016/j.syapm.2016.08.005 PMID: 27665238


Herbivorax saccincola gen. nov., sp. nov., a cellulolytic, anaerobic, thermophilic bacterium isolated via in sacco enrichments from a lab scale biogas reactor. Int. J. Syst. Evol. Microbiol. 66: 4458-4463. * corresponding author doi: 10.1099/ijsem.0.001374 PMID: 27499077


Koeck DE, Maus I, Wibberg D, Winkler A, Zverlov VV, Liebl W, Pühler A, Schwarz WH, Schlüter A (2016) Complete genome sequence of Herbinix luporum SD1D, a new cellulose degrading bacterium isolated from a thermophilic biogas reactor. Genome Announc. 4(4): e00687-16. doi: 10.1128/genomeA.00687-16 PMID: 27445379


Koeck DE, Maus I, Wibberg D, Winkler A, Zverlov VV, Liebl W, Pühler A, Schwarz WH, Schlüter A. (2016) Draft genome sequence of Propionispora sp. 2/2-37, a new mesophilic xylan degrading bacterium isolated from a mesophilic biogas reactor. GenomeA, 4(3): e00609-16. doi: 10.1128/genomeA.00609-16 PMID: 27340074


Koeck DE, Wibberg D, Maus I, Winkler A, Albersmeier A, Zverlov VV, Liebl W, Pühler A, Schwarz WH, Schlüter A. (2016) Corrigendum to "Complete genome sequence of the cellulolytic thermophile Ruminoclostridium cellulosi wild-type strain DG5 isolated from a thermophilic biogas plant" [J. Biotechnol. 188 (2014) 136-137]. J Biotechnol. 237:35. doi: 10.1016/j.jbiotec.2016.08.020 PMID: 27642063


Maus I, Koeck DE, Cibis KG, Hahnke S, Kim JS, Langer T, Kreubel J, Erhard M, Bremges A, Off S, Stolze Y, Jaenicke S, Goesmann A, Sczyrba A, Scherer P, König H, Schwarz WH, Zverlov VV, Liebl W, Pühler A, Schlueter A, Klocke M (2016) Unraveling the microbiome of a thermophilic biogas plant by metagenome and metatranscriptome analysis complemented by characterization of bacterial and archaeal isolates. Biotechnology for Biofuels 9:paper171. doi: 10.1186/s13068-016-0581-3 PMID: 27525040


Schiefner A, Angelov A, Liebl W, Skerra A. (2016) Structural basis for cellulose binding by the type A carbohydrate-binding module 64 of Spirochaeta thermophila. Proteins 84(6):855-858. doi: 10.1002/prot.25010 PMID: 26868291


Lebuhn M, Derenko J, Rademacher A, Helbig S, Munk B, Pechtl A, Stolze Y, Prowe S, Schwarz WH, Schlüter A, Liebl W, Klocke M (2016) DNA and RNA Extraction and Quantitative Real-Time PCR-Based Assays for Biogas Biocenoses in an Interlaboratory Comparison. Bioengineering 3:paper 7. doi: 10.3390/bioengineering3010007 PMID: 28952569


Koeck DE, Köllmeier T, Zverlov VV, Liebl W, Schwarz WH (2015) Differences in biomass degradation between newly isolated environmental strains of Clostridium thermocellum and heterogeneity in the size of the cellulosomal scaffoldin. Sys. Appl. Microbiol. 38(6):424-432. doi: 10.1016/j.syapm.2015.06.005 PMID: 26227216


Zverlov V, Prechtl R, Leis B, Held C, Liebl W, Schwarz W (2015) beta-Glucosidase-Varianten mit erhöhter Thermostabilität für den Einsatz im enzymatischen Biomasse-Abbau. Patentanmeldung. Amtl. Az DE 102015117534.7; PCT/EP2016/070804;  WO2017063787A1


Leis B, Heinze S, Angelov A, Pham VT, Thürmer A, Jebbar M, Golyshin PN, Streit WR, Daniel R, Liebl W (2015) Functional Screening of Hydrolytic Activities Reveals an Extremely Thermostable Cellulase from a Deep-Sea Archaeon. Frontiers Bioeng. Biotechnol. 3:paper 95. doi: 10.3389/fbioe.2015.00095 PMID: 26191525


Dib JR, Angelov A, Liebl W, Döbber J, Voget S, Schuldes J, Gorriti M, Farías ME, Meinhardt F, Daniel R (2015) Complete Genome Sequence of the linear plasmid pJD12 hosted by Micrococcus sp. D12, isolated from a high-altitude volcanic lake in Argentina. Genome Announc. 3(3): e00627-15. doi: 10.1128/genomeA.00627-15 PMID: 26067968


Leis B, Angelov A, Mientus M, Li H, Pham VTT, Lauinger B, Bongen P, Pietruszka J, Gonçalves LG, Santos H, Liebl W (2015) Identification of novel esterase-active enzymes from hot environments by use of the host bacterium Thermus thermophilus. Front. Microbiol., 6:paper 275. doi: 10.3389/fmicb.2015.00275 PMID: 25904908 Also published in Mazzoli R, Riedel K, Pessione E (eds.) Bioactive Compounds from Microbes, 2017, Frontiers Media SA. ISBN: 9782889451852


Koeck DE, Ludwig W, Wanner G, Zverlov VV, Liebl W, Schwarz WH (2015) Herbinix hemicellulosilytica, gen. nov., sp. nov., a thermophilic cellulose-degrading bacterium isolated from a thermophilic biogas reactor. Int J Syst Evol Microbiol. 65:2365-2371. doi: 10.1099/ijs.0.000264 PMID: 25872956


Koeck DE, Wibberg D, Winkler A, Zverlov VV, Liebl W, Puehler A, Schwarz WH, Schlueter A (2015) Draft genome sequence of Herbinix hemicellulosilytica T3/55T, a new thermophilic cellulose degrading bacterium isolated from a thermophilic biogas reactor. J. Biotechnol. 214:59-60. doi: 10.1016/j.jbiotec.2015.07.022 PMID: 26253960


Li H, Angelov A, Pham VT, Leis B, Liebl W. (2015) Characterization of chromosomal and megaplasmid partitioning loci in Thermus thermophilus HB27. BMC Genomics 16:paper 317. doi: 10.1186/s12864-015-1523-3 PMID: 25909452


Angelov A, Bergen P, Nadler F, Hornburg P, Lichev A, Übelacker M, Pachl F, Küster B, Liebl W (2015) Novel Flp pilus biogenesis-dependent natural transformation. Front. Microbiol. 6:paper 84. doi: 10.3389/fmicb.2015.00084 PMID: 25713572


Koeck DE, Koellmeier T, Schiffner S, Zverlov VV, Liebl W, Schwarz WH (2015) Differences in biomass degradation between newly isolated environmental strains of Clostridium thermocellum and heterogeneity in the size of the cellulosomal scaffoldin. System. Appl. Microbiol. 38:424-432. DOI: 10.1016/j.syapm.2015.06.005 PMID: 26227216


Kostner D, Luchterhand B, Junker A, Volland S, Daniel R, Büchs J, Liebl W, Ehrenreich A (2015) The consequence of an additional NADH dehydrogenase paralog on the growth of Gluconobacter oxydans DSM3504. Appl. Microbiol. Biotechnol. 99:375-386. doi: 10.1007/s00253-014-6069-9 PMID: 25267158


Hönicke D, Lütke-Eversloh T, Liu Z, Lehmann D, Liebl W, Ehrenreich A (2014) Chemostat cultivation and transcriptional analyses of Clostridium acetobutylicum mutants with defects in the acid and acetone biosynthetic pathways. Appl Microbiol Biotechnol 98:9777-9794. doi: 10.1007/s00253-014-6040-9 PMID: 25280743


Koeck DE, Wibberg D, Maus I, Winkler A, Albersmeier A, Zverlov VV, Pühler A, Schwarz WH, Liebl W, Schlüter A (2014) First draft genome sequence of the amylolytic Bacillus thermoamylovorans wild-type strain 1A1 isolated from a thermophilic biogas plant. J. Biotechnol. 192A:154-155. doi: 10.1016/j.jbiotec.2014.09.017 PMID: 25270021


Liebl W, Angelov A, Juergensen J, Chow J, Loeschcke A, Drepper T, Classen T, Pietruszka J, Ehrenreich A, Streit WR, Jaeger KE (2014) Alternative hosts for functional metagenome analysis. Appl. Microbiol. Biotechnol. 98:8099-8109. doi: 10.1007/s00253-014-5961-7 PMID: 25091044 Erratum in Appl Microbiol Biotechnol. 98:9149.


Leis B, Angelov A, Li H, Liebl W (2014) Genetic analysis of lipolytic activities in Thermus thermophilus HB27. J. Biotechnol. 191:150-157. doi: 10.1016/j.jbiotec.2014.07.448 PMID: 25102235


Koeck DE, Wibberg D, Maus I, Winkler A, Albersmeier A, Zverlov VV, Liebl W, Pühler A, Schwarz WH, Schlüter A (2014) Complete genome sequence of the cellulolytic thermophile Ruminiclostridium cellulosi wild-type strain DG5 isolated from a thermophilic biogas plant. J. Biotechnol. 188C:136-137. doi: 10.1016/j.jbiotec.2014.08.024 PMID: 25173616


Lesiak J, Liebl W, Ehrenreich A (2014) Development of an in vivo methylation system for the solventogen Clostridium saccharobutylicum NCP 262 and analysis of two endonuclease mutants. J. Biotechnol. 188C:97-99. doi: 10.1016/j.jbiotec.2014.07.005 PMID: 25087740


Koeck DE, Zverlov VV, Liebl W, Schwarz WH (2014) Comparative genotyping of Clostridium thermocellum strains isolated from biogas plants: Genetic markers and characterization of cellulolytic potential. Syst. Appl. Microbiol. 37:311-319. doi: 10.1016/j.syapm.2014.05.006 PMID: 24951450


Kurka H, Ehrenreich A, Ludwig W, Monot M, Rupnik M, Barbut F, Dupuy B, Liebl W (2014) Sequence similarity of Clostridium difficile strains by analysis of conserved genes and genome content is reflected by their ribotype affiliation, PLoS ONE 9(1): e86535. do10.1371/journal.pone.0086535 PMID: 24482682


Poehlein A, Hartwich K, Krabben P, Ehrenreich A, Liebl W, Dürre P, Gottschalk G, Daniel R (2013) Complete genome sequence of the solvent producer Clostridium saccharobutylicum NCP262 (DSM 13864). Genome Announc 00997-13. doi: 10.1128/genomeA.00997-13 PMID: 24285650


Angelov A, Li H, Geissler A, Leis B, Liebl W (2013) Toxicity of indoxyl derivative accumulation in bacteria and its use as a new counterselection principle. Syst. Appl. Microbiol. 36:585-592. doi: 10.1016/j.syapm.2013.06.001 PMID: 23871391


Stark TD, Angelov A, Hofmann M, Liebl W, Hofmann T (2013) Comparative direct infusion and ion mobility separation-quan-Time-of-Flight mass spectrometric profiling of Thermus thermophilus wild-type and mutant ?cruC carotenoid extracts, Anal. Bioanal. Chem. 405:9843-9848. doi: 10.1007/s00216-013-7426-8 PMID: 24213964


Mientus M, Brady S, Angelov A, Zimmermann P, Wemheuer B,  Schuldes J,  Daniel R, Liebl W (2013)  Thermostable xylanase and ß-glucanase derived from the metagenome of the Avachinsky crater in Kamchatka (Russia), Curr. Biotechnol. 2:284-293.


Kostner D, Peters B, Mientus M, Liebl W, Ehrenreich A (2013) Importance of codB for new codA-based markerless gene deletion in Gluconobacter strains. Appl. Microbiol. Biotechnol. 97:8341-8349. doi: 10.1007/s00253-013-5164-7 PMID: 23955475


Lee NM, Porter ML, Liebl W, Engel AS (2013) Cave biofilm metagenomics. In Nelson KE (ed.) Encyclopedia of Metagenomics, Springer Verlag.


Rachinger M, Pfaffenhäuser M, Bongaerts J, Evers S, Maurer K-H, Daniel R, Liebl W, Liesegang H, Ehrenreich A (2013) Size unlimited markerless deletions by a transconjugative plasmid system in Bacillus licheniformis. J. Biotechnol. 167:365-369. doi: 10.1016/j.jbiotec.2013.07.026 PMID: 23916947


Peters B, Mientus M, Kostner D, Liebl W, Ehrenreich A (2013) Characterization of membrane-bound dehydrogenases from Gluconobacter oxydans 621H via whole-cell activity assays using multi-deletion strains. Appl. Microbiol. Biotechnol. 97:6397-6412. doi: 10.1007/s00253-013-4824-y PMID: 23519735


Leis B, Angelov A, Liebl W (2013) Screening and expression of genes from metagenomes. Adv. Appl. Microbiol. 83: 1-68. doi: 10.1016/B978-0-12-407678-5.00001-5 PMID: 23651593


Peters B, Junker A, Brauer K, Mühlthaler B, Kostner D, Mientus M, Liebl W, Ehrenreich A (2013) Deletion of pyruvate decarboxylase by a new method for efficient markerless gene deletions in Gluconobacter oxydans. Appl. Microbiol. Biotechnol. 97:2521-2530. doi: 10.1007/s00253-012-4354-z PMID: 22940799


Poehlein A, Zverlov V, Daniel R, Schwarz W, Liebl W (2013) Complete genome sequence of Clostridium stercorarium subsp. stercorarium DSM 8532, a thermophilic degrader of plant cell wall fibres. Genome Announce e00073-13. doi: 10.1128/genomeA.00073-13 PMID: 23516204


Dib JR, Liebl W, Wagenknecht M, Farías ME, Meinhardt F (2013) Extrachromosomal elements in Micrococcus. Appl. Microbiol. Biotechnol. 97:63-75. doi: 10.1007/s00253-012-4539-5 PMID: 23138713


Hoppert M, Valdez M, Enseleit M, Theilmann W, Valerius O, Föst C, Liebl W (2012) Structure-function analysis of the Dictyoglomus cell envelope. Sys. Appl. Microbiol. 35:279-90. doi: 10.1016/j.syapm.2012.06.004 PMID: 22824581


Liebl W, Daniel R, Steinbüchel A (2012) Involvement of two latex clearing proteins during rubber degradation and insights into the further degradation pathway revealed by the genome sequence of Gordonia polyisoprenivorans strain VH2. Appl. Environ. Microbiol. 78:2874-2887. doi: 10.1128/AEM.07969-11 PMID: 22327575


Lee NM, Meisinger DB, Aubrecht R, Kovacik L, Saiz-Jimenez C, Baskar S, Baskar R, Liebl W, Porter M, Summers-Engel A (2012) Life in Caves and Karst Environments. In Bell EM (ed.) Life at Extremes: Environments, Organisms and Strategies for Survival. Chapter 17, p. 320-344. CABI Publishing UK


Meola M, Lee NM, Heim C, Queric NV, Braissant O, Ionescu D, deBeer D, Löffler FE, Thiel V, Reitner J, Liebl W (2012) Astrobiologiocal lessons from the ancient iron-oxidizing genus Gallionella. Paleontological J 46(9):1071-1072.


Ilmberger N, Meske D, Jürgensen J, Mientus M, Angelov A, Schulte M, Barthen P, Ingnatiev N, Liebl W, Schmitz RA, Streit WR (2012) Ionic liquid tolerant cellulases – linking thermostability and halotolerance. Appl. Microbiol. Biotechnol. 95:135-46. doi: 10.1007/s00253-011-3732-2 PMID: 22143172


Thürmer A, Voigt B, Angelov A, Hecker M, Liebl W (2011) Proteomic analysis of the extreme thermoacidophilic archaeon Picrophilis torridus during growth at pH and temperature values close to its growth limit. Proteomics 11:4559-4568. doi: 10.1002/pmic.201000829 PMID: 22114103


Angelov A, Voss J, Liebl W (2011) Characterization of plasmid pPO1 from the hyperacidophile Picrophilus oshimae. Archaea 2011:723604. doi: 10.1155/2011/723604 PMID: 21941462


Vogel RF, Pavlovic M, Ehrmann MA, Wiezer A, Liesegang H , Offschanka S , Voget S, Angelov A, Böcker G, Liebl W (2011) Genomic analysis reveals Lactobacillus sanfranciscensis as stable element in traditional sourdoughs. Microb. Cell. Fact. 10 Suppl. 1:S6. doi: 10.1186/1475-2859-10-S1-S6 PMID: 21995419


Angelov A, Loderer C, Pompei S, Liebl W (2011) Novel family of carbohydrate-binding modules revealed by the genome sequence of Spirochaeta thermophila DSM 6192. Appl. Environ. Microbiol. 77:5483-5489. doi: 10.1128/AEM.00523-11 PMID: 21685171


Grimmler C, Janssen H, Krausse D, Fischer RJ, Bahl H, Dürre P, Liebl W, Ehrenreich A (2011) Genome-wide gene expression analysis of the switch between acidogenesis and solventogenesis  in continuous cultures of Clostridium acetobutylicum. J. Mol. Microbiol. Biotechnol. 20:1-15. doi: 10.1159/000320973 PMID: 21212688


Liebl W (2011) Synthetic biology: Perspectives. Nachr. Chemie 59(3):303-308.


Liebl W (2010) Metagenomics. In Reitner J, Thiel V (ed.) Enzyclopedia of Geobiology. Springer.


Lee NM, Meisinger, DB, Löffler FE, Schmid M, Ludwig W, Liebl W, Schleifer KH (2010) Fluorescence in situ hybridization. In Reitner J, Thiel V (ed.) Enzyclopedia of Geobiology. Springer.


Angelov A, Liebl S, Ballschmiter M, Bömeke M, Lehmann R, Liesegang H, Daniel R, Liebl W (2010) Genome sequence of the polysaccharide-degrading, thermophilic anaerobe Spirochaeta thermophila DSM 6192. J. Bacteriol. 192(24):6492-6493. doi: 10.1128/JB.01023-10 PMID: 20935097


Grimmler C, Held C, Liebl W, Ehrenreich A (2010) Transcriptional analysis of catabolite repression in Clostridium acetobutylicum growing on mixtures of D-glucose and D-xylose. J. Biotechnol. 150:315-323. doi: 10.1016/j.jbiotec.2010.09.938 PMID: 20883732


Köpke M, Held C, Hujer S, Liesegang H, Wiezer A, Wollherr A, Ehrenreich A, Liebl W, Gottschalk G, Dürre P (2010) Clostridium ljungdahlii represents a microbial production platform based on syngas. Proc. Natl. Acad. Sci. USA 107(29):13087-13092. doi: 10.1073/pnas.1004716107 PMID: 20616070 Erratum in: Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15305.


Klee SR, Brzuszkiewicz EB, Nattermann H, Brüggemann H, Dupke S, Wollher A, Franz T, Pauli G, Appel B, Liebl W, Couacy-Hymann E, Boesch C, Meyer F-D, Leendertz FH, Ellerbrok H, Gottschalk G, Grunow R, Liesegang H (2010) Genome of a Bacillus isolate causing anthrax in chimpanzees combines chromosomal properties of B. cereus with B. anthracis virulence plasmids. PLoS One 5(7): e10986. doi: 10.1371/journal.pone.0010986 PMID: 20634886


Voss J, Ehrenreich A and Liebl W (2010) Characterization and inactivation of the membrane-bound polyol dehydrogenase in Gluconobacter oxydans DSM 7145 reveals a role in meso-erythritol oxidation. Microbiology (SGM) 156:1890-1899. doi: 10.1099/mic.0.037598-0 PMID: 20223802


Drzewiecki K, Angelov A, Ballschmiter M, Tiefenbach K-J, Sterner R, and Liebl W (2010) Hyperthermostable acetyl xylan esterase. Microbial Biotechnology 3(1): 84-92. doi: 10.1111/j.1751-7915.2009.00150.x PMID: 21255309


Wagner-Döbler I, Ballhausen B, Baumgart M, Brinkhoff T, Buchholz I, Bunk B, Cypionka H, Daniel R, Drepper T, Gerdts G, Hahnke S, Han C, Jahn D, Kalhoefer D, Kiss H, Klenk H-P, Kyrpides N, Liebl W, Liesegang H, Meincke L, Pati A, Petersen J, Piekarski T, Pommerenke C, Pradella S, Pukall R, Rabus R, Stackebrandt E, Thole S, Thompson L, Tielen P, Tomasch J, von Jan M, Wanphrut N, Wichels A, Zech H, and Simon M (2010) The complete genome sequence of the algal symbiont Dinoroseobacter shibae – a hitchhiker`s guide to life in the sea. ISME Journal 4: 61-77. doi: 10.1038/ismej.2009.94 PMID: 19741735


Liebl W (2009) Biotechnologische Nutzung der Vielfalt – Neue Wirtsorganismen für funktionelle (Meta)Genomanalyse. GENOMXPRESS 3.09: 13-16.


Angelov A, Mientus M, Liebl S, Liebl W (2009) A two-host fosmid system for functional screening of (meta)genomic libraries from extreme thermophiles. Sys. Appl. Microbiol. 32:177-185. doi: 10.1016/j.syapm.2008.01.003 PMID: 19285378


Antranikian G, Ruepp A, Gordon PMK, Ballschmiter M, Zibat A, Stark M, Sensen CW, Frishman D, Liebl W, and Klenk H-P (2009) Rapid access to genes of biotechnologically useful enzymes by partial genome sequencing: the thermoalkaliphile Anaerobranca gottschalkii. J. Mol. Microbiol. Biotechnol. 16:81-90. doi: 10.1159/000142896 PMID: 18957864


Hauer K, Meisinger DB, Pavlekovic M, Thomas SH, Kniggendorf AK, Chee-Sanford J, Sanford R, Lebron CA, Liebl W, Loeffler FE, Lee NM (2009) Novel tools for in situ detection of biodiversity and function of dechlorinating and uranium-reducing bacteria in contaminated environments. Geochim. Cosmochim. Acta 73(13):A502-A502 (meeting abstract)


Tzvetkov MV and Liebl W (2008) Phytate utilization by genetically engineered lysine-producing Corynebacterium glutamicum. J. Biotechnol. 134:211-217. doi: 10.1016/j.jbiotec.2008.02.005 PMID: 18374441


Liebl W, Winterhalter C, Baumeister W, Armbrecht M, and Valdez M (2008) Xylanase attachment to the cell surface of the hyperthermophilic bacterium Thermotoga maritima, J. Bacteriol. 190: 1350-1358. doi: 10.1128/JB.01149-07 PMID: 18083821


Liebl W, Porstendörfer D, and Hoppert M (2007) Forensische Mikrobiologie. In B. Herrmann and K.S. Saternus (ed.) Biologische Spurenkunde Band I, Kriminalbiologie. pp. 245-258. Springer, Heidelberg.


Angelov A, and Liebl W (2007) Genomics of acidophiles. In C. Gerday and N. Glansdorff (ed.)  Physiology and Biochemistry of Extremophiles. pp. 279-294. ASM Press, Washington.


Angelov A, Putyrski M and Liebl W (2006) Molecular and biochemical characterisation of alpha-glucosidase and alpha-mannosidase and their clustered genes from the thermoacidophilic archaeon Picrophilus torridus, J. Bacteriol., 188: 7123-7131. doi: 10.1128/JB.00757-06 PMID: 17015651


Kleine J, and Liebl W (2006) Comparative characterization of deletion derivatives of the modular xylanase XynA of Thermotoga maritima. Extremophiles 10:373-381. DOI: 10.1007/s00792-006-0509-0 PMID: 16550304


Angelov A, and Liebl W (2006) Insights into extreme thermoacidophily based on genome analysis of Picrophilus torridus and other thermoacidophilic archaea. J. Biotechnol. 126: 3-10. doi: 10.1016/j.jbiotec.2006.02.017 PMID: 16621083


Klopprogge C, Zelder O, and Liebl W (2006) Process for the production of amino acids without trehalose. European Patent, 03795933.5-1212-EP0314580.


Ballschmiter M, Fütterer O, and Liebl W (2006) Identification and characterization of a novel intracellular alkaline alpha-amylase from the hyperthermophilic bacterium Thermotoga maritima. Appl. Environ. Microbiol. 72: 2206-2211. doi: 10.1128/AEM.72.3.2206-2211.2006 PMID: 16517673


Dickmanns A, Ballschmiter M, Liebl W, and Ficner R (2006) Structure of the novel alpha-amylase AmyC from Thermotoga maritima. Acta Crystall. 62: 262-270. doi: 10.1107/S0907444905041363 PMID: 16510973
Liebl W (2005) Corynebacterium Taxonomy. In: Handbook of Corynebacterium glutamicum (L. Eggeling and M. Bott, ed.), CRC Press, pp. 9-34.


Ballschmiter M, Armbrecht M, Ivanova K, Antranikian G, and Liebl W (2005) AmyA, an alpha-amylase with ß-cyclodextrin-forming activity, and AmyB from the thermoalkaliphile Anaerobranca gottschalkii: two alpha-amylases adapted to their different cellular localization. Appl. Environ. Microbiol. 71: 3709-3715. doi: 10.1128/AEM.71.7.3709-3715.2005 PMID: 16000780


Angelov A, Fütterer O, Valerius O, Braus GH, and Liebl W (2005) Properties of the recombinant glucose/galactose dehydrogenase from the extreme thermoacidophile, Picrophilus torridus. FEBS J. (Eur. J. Biochem.) 272:1054-1062. DOI: 10.1111/j.1742-4658.2004.04539.x PMID: 15691337


Fütterer O, Angelov A, Liesegang H, Gottschalk G, Schleper C, Schepers B, Dock C, Antranikian G, and Liebl W (2004) Genome sequence of Picrophilus torridus and its implications for life around pH 0. Proc. Natl. Acad. Sci. U.S.A. 101:9091-9096. doi: 10.1073/pnas.0401356101 PMID: 15184674


Liebl W (2004) Genomics taken to the extreme. Nature Biotechnology 22:524-525. doi:10.1038/nbt0504-524 PMID: 15122289


Klopprogge C, Zelder O, Kroeger B, Schroeder H, Haefner S, Liebl W, Schröder H, Kröger B, Hafner S, Hofner S (2004) Producing amino acid, e.g. L-lysine, and L-glutamate comprises culturing microorganism of genus Corynebacterium or Brevibacterium (partially) deficient in gene locus or loci. Patent Number(s): WO2004057009-A1 ; DE10261579-A1 ; AU2003298216-A1 ; EP1578979-A1 ; BR200317507-A ; US2006063239-A1 ; JP2006511216-W ; CN1732268-A ; EP1918384-A1 ; US2008166774-A1 ; JP2008200046-A ; CN101255452-A


Bertoldo C, Armbrecht M, Becker F, Schäfer T, Antranikian G, and Liebl W (2004) Cloning, sequencing and characterization of thermoalkalistable pullulanase type I from Anaerobranca gottschalkii. Appl. Environ. Microbiol. 70:3407-3416. doi: 10.1128/AEM.70.6.3407-3416.2004 PMID: 15184138


Lunina NA, Berezina OV, Veith B, Zverlov VV, Vorobjeva IP, Chekanovskaya LA, Khromov IS, Raasch C, Liebl W, and Velikodvorskaya GA (2003) A cluster of Thermotoga neapolitana genes involved in the degradation of starch and maltodextrins: the expression of the aglB and aglA genes in E. coli and the properties of the recombinant enzymes. Mol. Biol. 37:810-819.


Berezina OV, Lunina NA, Zverlov VV, Naumoff DG, Liebl W, and Velikodvorskaya GA (2003) Thermotoga neapolitana gene clusters involved in the degradation of starch and maltodextrins: molecular structure of the locus. Mol. Biol. 37:801-809. PMID: 14593916


Thiemann V, Antranikian G, Klenk H-P, Vollstedt A, Freudl R, Jürgens C, Sterner R, and Liebl W (2003) Das thermoalkaliphile Bakterium Anaerobranca gottschalkii als Quelle stabiler Enzyme zur Herstellung hochwertiger Kohlenhydrate. Transkript 9:90-93 (Sonderheft „Nachhaltige Biokatalyse“).


Pompejus M, Klopprogge C, Zelder O, and Liebl W (2003) New plasmid unable to replicate in a target organism, useful for marker-free mutation of e.g. Corynebacterium for improved fermentative production of fine chemicals / Verfahren zur Herstellung eines Marker-freien mutierten Zielorganismus sowie dafür geeignete Plasmidvektoren, Patentanmeldung, Nr. 02794516.1-2405-EP0208231. Patent Number(s): WO2003014362-A2 ; DE10137815-A1 ; EP1417317-A2 ; KR2004020080-A ; US2004171160-A1 ; AU2002355460-A1 ; JP2004538003-W ; WO2003014362-A3


Veith B, Zverlov VV, Lunina NA, Berezina OV, Raasch C, Velikodvorskaya GA, and Liebl W (2003) Comparative analysis of the recombinant ?-glucosidases from the Thermotoga neapolitana and Thermotoga maritima maltodextrin utilization gene clusters. Biocatal. Biotransform. 21:147-158.


Tzvetkov M, Klopprogge C, Zelder O, and Liebl W (2003) Genetic dissection of trehalose biosynthesis in Corynebacterium glutamicum: inactivation of trehalose production leads to impaired growth and an altered cell wall lipid composition. Microbiology 149:1659-1673. PMID: 12855718


Lodge JA, Maier T, Liebl* W, Hoffmann V, and Sträter* N (2003) Crystal structure of Thermotoga maritima alpha-glucosidase AglA defines a new clan of NAD+-dependent glycosidases. J. Biol. Chem., 278:19151-19158.  * equal, responsible and corresponding authorship doi: 10.1074/jbc.M211626200 PMID: 12588867


Liebl W (2002) Extremophile: Mikroorganismen unter Extrembedingungen. Georgia Augusta 1:98-103.


Roujeinikova A, Raasch C, Sedelnikova S, Liebl W and Rice DW (2002) Crystal structure of Thermotoga maritima 4-alpha-glucanotransferase and its acarbose complex: implications for substrate specificity and catalysis. J. Mol. Biol. 321:149-162. DOI: 10.1016/S0022-2836(02)00570-3 PMID: 12139940


Raasch C, Roujeinikova A, Meissner H, Rice DW, and Liebl W (2002) Biochemical Properties and Structural Features of the Thermostable Maltodextrin Transglycosidases from Thermotoga maritima. Biologia 57/Suppl.11:101-108. ISSN: 13356399


Liebl W, Kloos WE, and Ludwig W (2002) Plasmid-borne macrolide resistance in Micrococcus luteus. Microbiology 148:2479-2487. doi: 10.1099/00221287-148-8-2479 PMID: 12177341


Raasch C, Armbrecht M, Streit W, Höcker B, Sträter N, and Liebl W (2002) Identification of residues important for NAD+-binding by the Thermotoga maritima alpha-glucosidase AglA, a member of glycoside hydrolase family 4. FEBS Lett. 517:267-271. DOI: 10.1016/S0014-5793(02)02641-8 PMID: 12062450


Antranikian G, Klenk H-P, Freudl R, Sterner R, and Liebl W (2001) Extremophile Mikroorganismen als Quelle stabiler Biokatalysatoren. In S. Heiden und R. Erb (eds.) Biokatalyse, Spektrum akademischer Verlag, Heidelberg.


Liebl W (2001) Corynebacterium Nonmedical. In M. Dworkin et al. (eds.) The Prokaryotes. An Evolving Electronic Resource for the Microbiological Community, 3rd edition (latest update release 3.8, December 2001), Springer-Verlag, New York.


Roujeinikova A, Raasch C, Burke J, Baker PJ, Liebl W and Rice DW (2001) The crystal structure of Thermotoga maritima maltosyltransferase and its implications for the molecular basis of the novel transfer specificity. J. Mol. Biol. 312:119-131. doi: 10.1006/jmbi.2001.4944 PMID: 11545590


Roujeinikova A, Raasch C, Sedelnikova S, Liebl W and Rice DW (2001) Crystallization and preliminary X-ray crystallographic studies on 4-a-glucanotransferase from Thermotoga maritima. Acta Crystall. D57 :1046-1047. doi: 10.1107/S0907444901007740 PMID: 11418778


Sterner R, and Liebl W (2001) Thermophilic adaptation of proteins. Crit. Rev. Biochem. Mol. Biol. 36:39-106. DOI: 10.1080/20014091074174 PMID: 11256505


Entcheva P, Liebl W, Johann A, Hartsch T, and Streit W (2001) Direct cloning from enrichment cultures, a reliable strategy for isolation of complete operons and genes from microbial consortia. Appl. Environ. Microbiol. 67:89-99. DOI: 10.1128/AEM.67.1.89-99.2001 PMID: 11133432


Miller ES Jr, Parker KN, Liebl W, Lam D, Callen W, Snead MA, Mathur E J, Short JM, and Kelly RM (2001) alpha-Galactosidases from Thermotoga species. Meth. Enzymol. 330:246-260. PMID: 11210503


Liebl W (2001) Cellulolytic enzymes from Thermotoga species. Meth. Enzymol. 330:290-300. doi: 10.1016/S0076-6879(01)30383-X PMID: 11210507


Streit W, Hofmann K, and Liebl W (2000) Molecular characterization of the Sinorhizobium meliloti nlpD gene. Arch. Microbiol. 174:292-295. doi: 10.1007/s002030000205


Burke J, Roujeinikova A, Baker PJ, Sedelnikova S, Raasch C, Liebl W, and Rice DW (2000) Crystallization and preliminary X-ray crystallographic studies on maltosyltransferase from Thermotoga maritima. Acta Crystall. D56:1049-1050. doi: 10.1107/S0907444900007708 PMID: 10944350


Raasch C, Streit W, Schanzer J, Bibel M, Gosslar U, and Liebl W (2000) Thermotoga maritima AglA, an extremely thermostable NAD+-, Mn2+-, and thiol-dependent alpha-glucosidase. Extremophiles 4:189-200. DOI: 10.1007/PL00010711 PMID: 10972187


Meissner K, Wassenberg D, and Liebl W (2000) The thermostabilising domain of the modular xylanase XynA of Thermotoga maritima represents a novel type of binding domain with affinity for soluble xylan and mixed-linkage beta-1,2/beta-1,4-glucan. Mol. Microbiol, 36:898-912. DOI: 10.1046/j.1365-2958.2000.01909.x PMID: 10844677


Wassenberg D, Liebl W, und Jaenicke R (2000) Maltose-binding protein from the hyperthermophilic bacterium Thermotoga maritima: Stability and binding properties. J. Mol. Biol., 295:279-288. DOI: 10.1006/jmbi.1999.3367 PMID: 10623526


Kriegshäuser G, and Liebl W (2000) Pullulanase from the hyperthermophilic bacterium Thermotoga maritima: Purification by ß-cyclodextrin affinity chromatography. J. Chromatogr. B 737:245-251. PMID: 10681061


Hofmann K, Heinz EB, Charles TC, Hoppert M, Liebl W, and Streit WR (2000) Sinorhizobium meliloti strain 1021 bioS and bdhA gene transcriptions are both affected by biotin available in defined medium. FEMS Microbiol. Lett. 182:41-44. DOI: 10.1111/j.1574-6968.2000.tb08870.x PMID: 10612728


Berezina OV, Zverlov VV, Lunina NA, Chekanovskaya LA, Dubinina EN, Liebl W, and Velikodvorskaya GA (1999) Gene and properties of thermostable 4-alpha-glucanotransferase of Thermotoga neapolitana. Mol. Biol. 33:801-806.


Liebl W (1999) Glycosyl hydrolases and transferases of saccharide utilisation of hyperthermophilic microorganisms. In: Biochemical principles and mechanisms of biosynthesis and biodegradation of polymers (A. Steinbüchel, ed.), pp. 239-247, Wiley-VCH.


Meissner H, and Liebl W (1998) Thermotoga maritima maltosyltransferase, a novel type of maltodextrin glycosyltransferase acting on starch and malto-oligosaccharides. Eur. J. Biochem. 250:1050-1058. DOI: 10.1046/j.1432-1327.1998.2581050.x PMID: 9990324


Thoma R, Liebl W, Kirschner K, and Sterner R (1998) A histidine gene cluster of the hyperthermophile Thermotoga maritima: sequence analysis and evolutionary significance. Extremophiles, 2:379-389. DOI: 10.1007/s007920050082 PMID: 9827326


Liebl W, Brem D, and Gotschlich A (1998) Analysis of the gene for ß-fructosidase (invertase, inulinase) of the hyperthermophilic bacterium Thermotoga maritima, and characterisation of the enzyme expressed in Escherichia coli. Appl. Microbiol. Biotechnol. 50:55-64. DOI: 10.1007/s002530051256 PMID: 9720201


Zverlov VV, Liebl W, Bachleitner M, and Schwarz W  (1998) Nucleotide sequence of arfB of Clostridium stercorarium, and prediction of catalytic residues of alpha-L-arabinofuranosidases based on local similarity with several families of glycosyl hydrolases. FEMS Microbiol. Lett. 164:337-343.  DOI: 10.1111/j.1574-6968.1998.tb13107.x PMID: 9682483


Liebl W, Wagner B, und Schellhase J (1998) Properties of an alpha-galactosidase, and structure of its gene, galA, within an alpha- and ß-galactoside utilization gene cluster of the hyperthermophilic bacterium Thermotoga maritima. System. Appl. Microbiol. 21:1-11. DOI: 10.1016/S0723-2020(98)80002-7 PMID: 9741105


Bibel M, Brettl C, Gosslar U, Kriegshäuser G, and Liebl W (1998) Isolation and analysis of genes for amylolytic enzymes of the hyperthermophilic bacterium Thermotoga maritima. FEMS Microbiol. Lett. 158:9-15. DOI: 10.1111/j.1574-6968.1998.tb12793.x PMID: 9453151


Wassenberg D, Schurig H, Liebl W, and Jaenicke R (1997) Xylanase XynA from the hyperthermophilic bacterium Thermotoga maritima: Structure and stability of the recombinant enzyme and its isolated cellulose-binding domain. Protein Science 6:1718-1726. DOI: 10.1002/pro.5560060812 PMID: 9260284


Sinskey AJ, Follettie MT, Liebl W, and Peoples OP (1997) Glutamicum Threonine Biosynthetic Pathway. United States Patent; Date of Patent: Jun. 24, 1997; Patent Number: 5,641,660.


Kort R, Liebl W, Labedan B, Forterre P, Egge, RIL, and de Vos WM (1997) Glutamate dehydrogenase from the hyperthermophilic bacterium Thermotoga maritima: Molecular characterization and phylogenetic implications. Extremophiles 1:52-60. DOI: 10.1007/s007920050014 PMID: 9680336


Liebl W, Stemplinger I, and Ruile P (1997) Properties and gene structure of the Thermotoga maritima alpha-amylase AmyA, a putative lipoprotein of a hyperthermophilic bacterium. J. Bacteriol. 179:941-948. doi: 10.1128/jb.179.3.941-948.1997 PMID: 9006052


Ruile P, Winterhalter C, and Liebl W (1997) Isolation and analysis of a gene encoding alpha-glucuronidase, an enzyme with a novel primary structure involved in the breakdown of xylan. Mol. Microbiol. 23:267-279. DOI: 10.1046/j.1365-2958.1997.2011568.x PMID: 9044261


Liebl W, Ruile P, Bronnenmeier K, Riedel K, Lottspeich F, and Greif I (1996) Analysis of a Thermotoga maritima DNA fragment encoding two similar thermostable cellulases, CelA and CelB, and characterization of the recombinant enzymes. Microbiology 142:2533-2542. doi: 10.1099/00221287-142-9-2533 PMID: 8828221


Liebl W, Ruile P, Ossko E, Braun M, and Winterhalter C (1996) The enzymes of the hyperthermophilic bacterium Thermotoga maritima MSB8 for the degradation of xylan. In Srebotnik E and Messner K (eds.) Biotechnology in the Pulp and Paper Industry, pp. 491-495. Facultas-Universitätsverlag, Wien.


Sterner R, Dahm A, Darimont B, Ivens A, Liebl W, and Kirschner K (1995) (ß alpha)8- Barrel proteins of tryptophan biosynthesis in the hyperthermophile Thermotoga maritima. EMBO J. 14:4395-4402. DOI: 10.1002/j.1460-2075.1995.tb00118.x PMID: 7556082


Winterhalter C, and Liebl W (1995) Two extremely thermostable xylanases of the hyperthermophilic bacterium Thermotoga maritima strain MSB8. Appl. Environ. Microbiol. 61:1810-1815. PMID: 16535021


Bronnenmeier K, Kern A, Liebl W, and Staudenbauer W (1995) Purification of Thermotoga maritima enzymes for the degradation of cellulosic materials. Appl. Environ. Microbiol. 61:1399-1407. PMID: 7747960


Wind RD, Liebl W, Buitelaar RM, Penninga D, Dijkhuizen L, and Bahl H (1995) Cyclodextrin formation by the thermostable alpha-amylase of Thermoanaerobacterium thermosulfurigenes EM1. Reclassification of the enzyme as a cyclodextrin glycosyltransferase. Appl. Environ. Microbiol. 61:1257-1265. PMID: 7747949


Winterhalter C, Heinrich P, Candussio A, Wich G, and Liebl W (1995) Identification of a novel cellulose-binding domain within the multi-domain 120 kDa xylanase XynA of the hyperthermophilic bacterium Thermotoga maritima. Mol. Microbiol. 15:431-444. DOI: 10.1111/j.1365-2958.1995.tb02257.x PMID: 7783614


Liebl W, Winterhalter C, Heinrich P, and Candussio A (1994) Klonierung, Charakterisierung und Expression von extrem thermophilen Xylanasen. Patent.


Heinrich P, Huber W, and Liebl W (1994) Expression in Escherichia coli and structure of the gene encoding 4-alpha-glucanotransferase from Thermotoga maritima. Classification of maltodextrin glycosyltransferases into two distantly related enzyme subfamilies. System. Appl. Microbiol. 17:297-305. DOI: 10.1016/S0723-2020(11)80044-5


Huber W, and Liebl W (1994) Acceptor specificity of 4-alpha-glucanotransferase of Thermotoga maritima. Biocatalysis 11:105-115.


Liebl W, Gabelsberger J, and Schleifer KH (1994) Comparative amino sequence analysis of Thermotoga maritima ß-glucosidase (BglA) deduced from the nucleotide sequence of the gene indicates distant relationship between ß-glucosidases of the BGA family and other families of ß-1,4-glycosyl hydrolases. Mol. Gen. Genet. 242:111-115. PMID: 8277941


Ostendorp R, Liebl W, Schurig H, and Jaenicke R (1993) The L-lactate dehydrogenase gene of the hyperthermophilic bacterium Thermotoga maritima cloned by complementation in Escherichia coli. Eur. J. Biochem. 216:709-715. DOI: 10.1111/j.1432-1033.1993.tb18190.x PMID: 8404889


Brabetz W, Liebl W, and Schleifer KH (1993) Lactose permease of Escherichia coli catalyses active ß-galactoside transport in a Gram-positive bacterium. J. Bacteriol. 175:7488-7491. doi: 10.1128/jb.175.22.7488-7491.1993 PMID: 8226697


Gabelsberger J, Liebl W, and Schleifer KH (1993) Purification and properties of recombinant ß-glucosidase of the hyperthermophilic bacterium Thermotoga maritima. Appl. Microbiol. Biotechnol. 40:44-52. DOI: 10.1007/BF00170427


Gabelsberger J, Liebl W, and Schleifer KH (1993) Cloning and characterization of ß-galactoside and ß-glucoside hydrolysing enzymes of Thermotoga maritima. FEMS Microbiol. Lett. 109:131-138. DOI: 10.1111/j.1574-6968.1993.tb06157.x


Liebl W, Bohmann A, Zubek E, and Schleifer KH (1992) Isolation of genes for xylanase, ß-xylosidase, and arabinofuranosidase of Cellulomonas biazotea DSM 20112. In Visser J, Beldman G, Kusters- van Someren MA and Voragen AGJ (eds.) Progress in Biotechnology, Vol. 7, Xylans and Xylanases, pp. 475-478, Elsevier, Amsterdam.


Liebl W, Feil R, Gabelsberger J, Kellermann J, and Schleifer KH (1992) Purification and characterization of a novel thermostable 4-alpha-glucanotransferase of Thermotoga maritima cloned in Escherichia coli. Eur. J. Biochem. 207:81-88. DOI: 10.1111/j.1432-1033.1992.tb17023.x PMID: 1628664


Liebl W, Sinskey AJ, and Schleifer KH (1992) Expression, secretion, and processing of staphylococcal nuclease by Corynebacterium glutamicum. J. Bacteriol. 174: 1854-1861. doi: 10.1128/jb.174.6.1854-1861.1992 PMID: 1548234


Liebl W (1992) Corynebacterium non-medical. In Balows A, Trüper HG, Dworkin M, Harder W and Schleifer KH (eds.) The Prokaryotes. A Handbook on the Biology of Bacteria, Ecophysiology, Isolation, Identification, Applications. Second edition. Vol. II., pp. 1157-1171, Springer-Verlag, New York.


Eikmanns BJ, Kleinertz E, Liebl W, and Sahm H (1991) A family of Corynebacterium glutamicum/E. coli vectors for gene cloning, controlled gene expression, and promoter probing. Gene 102:93-98. DOI: 10.1016/0378-1119(91)90545-M PMID: 1864513


Brabetz W, Liebl W, and Schleifer KH (1991) Studies on the utilization of lactose by Corynebacterium glutamicum bearing the lactose operon of Escherichia coli. Arch. Microbiol. 155:607-612. DOI: 10.1007/BF00245357 PMID: 1953301


Liebl W, Ehrmann M, Ludwig W, and Schleifer KH (1991) Transfer of Brevibacterium divaricatum DSM 20297T, "Brevibacterium flavum" DSM 20411, "Brevibacterium lactofermentum" DSM 20412 and DSM 1412, and Corynebacterium lilium DSM 20137T to Corynebacterium glutamicum and their distinction by rRNA gene restriction patterns. Int. J. Syst. Bacteriol. 41:255-260. DOI: 10.1099/00207713-41-2-255 PMID: 1713055


Liebl W, and Schein B (1990) Isolation of restriction deficient mutants of Corynebacterium glutamicum. In Behrens D, Krämer P (eds.) Dechema Biotechnology Conferences, Vol. 4., pp. 323-327, VCH Verlagsgesellschaft, Weinheim.


Liebl W, Sinskey AJ (1990) Coryneform expression and secretion system. Patent Number(s): WO8809821-A1 ; WO8809821-A ; US4965197-A


Liebl W, Bayerl A, Schein B, Stillner U, and Schleifer KH (1989) High efficiency electroporation of intact Corynebacterium glutamicum cells. FEMS Microbiol. Lett. 65:299-304. DOI: 10.1111/j.1574-6968.1989.tb03677.x PMID: 2612892


Liebl W, Klamer R, and Schleifer KH (1989) Requirement of chelating compounds for the growth of Corynebacterium glutamicum in synthetic media. Appl. Microbiol. Biotechnol. 32:205-210. doi: 10.1007/BF00165889


Liebl W, Schleifer KH, and Sinskey AJ (1989) Secretion of heterologous proteins by Corynebacterium glutamicum. In Butler LO, Harwood C and Moseley BEB (eds.) Genetic Transformation and Expression. Intercept Limited, Andover, Hants, pp. 553-559.


Sinskey AJ, Follettie MT, Liebl W, Peoples O, Peoples OP (1988) Threonine production using recombinant vector. Patent Number(s): WO8809819-A2 ; WO8809819-A ; US5641660-A


Peoples OP, Liebl W, Bodis M, Maeng PJ, Folettie MT, Archer JA, and Sinskey AJ (1988) Nucleotide sequence and fine structural analysis of the Corynebacterium glutamicum hom-thrB operon. Mol. Microbiol. 2:63-72. DOI: 10.1111/j.1365-2958.1988.tb00007.x PMID: 2835591


Liebl W, and Sinskey AJ (1988) Molecular cloning and nucleotide sequence of a gene involved in the production of extracellular DNase by Corynebacterium glutamicum. In Ganesan AT and Hoch JA (eds.) Genetics and Biotechnology of Bacilli, Vol. 2, pp. 383-388, Academic Press, San Diego.


Liebl W, Rosenstein R, Götz F, and Schleifer KH (1987) Use of staphylococcal nuclease gene as DNA probe for Staphylococcus aureus. FEMS Microbiol. Lett. 44:179-184. doi: 10.1111/j.1574-6968.1987.tb02264.x


Liebl W, and Götz F (1986) Studies on lipase directed export of Escherichia coli ß-lactamase in Staphylococcus carnosus. Mol. Gen. Genet. 204:166-173. DOI: 10.1007/BF00330205 PMID: 3018441


Liebl W (1986) Expression fusionierter Gene und Sekretion ihrer Produkte in Staphylokokken. Dissertation, Technische Universität München.